The show introduced the popular cartoon characters Pinky and the Brain, who were subsequently spun off into their own TV series in 1995.
Animaniacs introduced a number of characters, including:
While episodes of the show did have their share of flops ("Mr. Skullhead," "Hip Hippos"), a surprisingly high number of well-written, outrageously funny cartoons were aired during the series, as the new madcap Warner Bros. animators merrily poked fun at everything and everyone, including their own fans ("The Please Please Pleese Get A Life Foundation").
While the show was very popular among younger viewers (the target demographic for Warner Bros.' TV cartoons), a great deal of the show's sly, subversive humor was definitely aimed at an adult audience. Adults responded in droves, giving the show cult-hit status and leading to one of the first Internet-based fandom cultures. During the show's prime, the Internet newsgroup alt.tv.animaniacs was an active, popular gathering place for fans of the show (most of whom were definitely adults) to discuss the latest antics of the Warner Brothers and the Warner Sister. The online popularity of the show did not go unnoticed by the show's producers, and several of the most active participants on the newsgroup were invited to the Warner Bros. Animation studios for informal get-togethers.
Animation fans consider Animaniacs the high point of the Warner Bros. revival of the 1990s that was inspired by the original Termite Terrace. After Animaniacs, Spielberg collaborated with Warner Bros. Animation for a third time to produce the short-lived series Freakazoid, along with the spin-off series Pinky and the Brain. Warner Bros. also produced two additional "zany" and "madcap" series in the later half of the decade entitled Histeria! and Detention, but neither of these series found a sizable audience, and they were both swiftly cancelled. Warner Bros. cut back the size of its animation studio (the high cost and relatively low profit of its animated feature films of the period also had an effect on the studio), and production on further Warner Bros. animated comedy series ceased. Animaniacs and Tiny Toon Adventures continued to rerun in syndication through the 1990s into the early 2000s.