The good supply of fresh water in the area led to the expansion of its population in the 19th century. Before 1996 the area around the bay was known as the Municipality of Botany, but since then it has been called the City of Botany Bay.
The small Mascot Aerodrome at Botany developed into Sydney (Kingsford Smith) Airport. Port Botany was built in 1930 and is now a container terminal.