It is a hub for Tunisair, Nouvel Air Tunisie, Tuninter and Tunisavia.
On May 7 of 2002 it suffered a tragedy as a Boeing 737 of Egyptair, attempting to land from Cairo crashed 4 miles from the airport, killing 14 of the 62 people on board.
The airport is named after the Carthage tombs located near Tunis.
Airlines serving this facility include: