Diethylcarbamazine
Diethylcarbamazine (DEC) is an
anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. DEC is indicated for treatment of individual patients with certain filarial
diseases. These diseases include: lymphatic filariasis caused by
infection with
Wuchereria bancrofti,
Brugia malayi, or
Brugia timori; tropical pulmonary eosinophilia; and
loiasis. DEC continues to be the mainstay for treatment of patients with lymphatic filariasis and
loiasis.
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