He was installed as bishop in Salamis on Cyprus in 367. He was versed in several languages including Hebrew, Syriac, Egyptian, Greek and Latin.
His most well-known book is Panarion which means "Medicine-chest" (also known as Adversus Haereses), a handbook for dealing with heretics, listing 80 heretical doctrines, some of which are not described in any other surviving documents from the time. This book was only recently (1987) translated into English.
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