It was originally the site of the Seneca Native American village of Kanadasaga. The village was abandoned following its destruction by the punitive Sullivan Expedition of 1779, but resettled by Europeans around 1793 as a town developed by the Pulteney Association.
Elizabeth Blackwell, the first woman to become qualified as a medical doctor in the United States studied here, graduating from the medical school at what was then Geneva College in 1849.
Hobart and William Smith Colleges, the successor institution to Geneva College.
The New York State Agricultural Experiment Station of Cornell University's College of Agriculture and Life Sciences