George was Jerry's best friend, but also neurotic, annoying, and juvenile. He lived with his parents, Estelle and Frank, a bitter couple who were almost as neurotic as their son.
In dealing with his friends, George was cheap and selfish. Along with Kramer, he would often concoct elaborate plots to weasle out of financial or legal obligations.
George's professional life was hilariously unstable and he was unable to remain in any job for any great length of time before making an embarrassing blunder and getting fired. Over the course of the series he worked for the New York Yankees, a gem polishing company, and countless other places.
For a brief period George was engaged to Susan Biddle Ross, a wealthy but often callous and dull woman. She was indirectly killed by George, who knowingly selected the cheapest envelope glue for their wedding invitations, despite the fact that he had heard such glues can be poisonous. (Because of the anthrax mail attacks of late 2001, this episode has been taken out of syndication.) Susan's parents never forgave him for this, and appointed him chairman of the Susan Biddle Ross foundation, to keep him trapped in their influences.