Lord Henry became betrothed to Anne Boleyn, the future second queen of Henry VIII probably in the spring of 1523, when Lord Percy was page to Cardinal Wolsey. On hearing the news, Lord Henry was scolded before his servants by the Cardinal, since permission for the marriage had not been sought from his father nor the king, who also had an interest due to the importance of the Northumberland earldom. His father refused permission for the marriage, and he later went on to marry Lady Mary Talbot, an unhappy marriage without issue. After spending his inheritance lavishly and transferring various estates to friends, the remainder of his estates went to the crown on his death. He was also a member of the jury that convicted Queen Anne of adultery.
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|width="30%" align="center"|Preceded by:
Henry Percy
|width="40%" align="center"|Earl of Northumberland
|width="30%" align="center"|Followed by:
Extinct
|}