Major Towns
Isoko is divided into two major local Government areas: Isoko South (with Irri as Local Government Headquarters) and Isoko North (with Ozoro as Headqaurters).
Some of the towns that make up Isoko are:
Ozoro, Olleh, Okpe, Ofagbe, Uzere, Irri, Idheze, Uro, Orie, Utue, Emede, Emevor, Otor-Owhe, Iyede, Ivrogbo, Illuelogbo and others.