Poydras wrote the first poetry published in Louisiana, in 1779. He was president of the first legislative council of the Territory of Orleans. He founded the Female Orphan Asylum in New Orleans, and was elected to the House, serving from March 4, 1809 - March 3, 1811. He was the president of the first state Constitutional Convention. He founded and endowed the Poydras Asylum, and died in Pointe Coupee, Louisiana. He was originally intered in Old St. Francis Cemetery, then he was reintered on the grounds of the Poydras High School, New Roads, Louisiana.