Kotoka has the capability of receiving airplanes up to the Boeing 747-400, and is the hub of Ghana Airways and DAS Air Cargo.
In 1999, world champion boxer Ike Quartey, apparently not a popular figure at home, was received with rocks and bottles by his country people at this airport after losing for the world Welterweight championship against Oscar De La Hoya, in what was catalogued as a mini riot.
Airlines landing at this airport include: