She appears in Shakespeare's play Macbeth, but the play, and the character of Lady Macbeth, are only very loosely based upon actual events. Lady Macbeth has become an archetypical character, providing the standard template for a wife pushing her husband to do harm through her own ambition.
Lady Macbeth of the Mtensk District is an opera by Shostakovitch, based on a novella of the same name by Nikolai Leskov.
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