Heading south from the M6, the M5 runs east of West Bromwich and west of Birmingham. The road continues past Bromsgrove, Worcester, Tewkesbury, Cheltenham, Gloucester, Bristol, Weston-Super-Mare, Bridgwater and Taunton on its way to Exeter.
The M5 closely follows the route of the A38 road. It has no connection with the A5 road.