Her first big hit was in Tezaab (1990). She also starred in popular films including Dil (1990), Beta (1991), and Khal Nayak (1993). Her high point was Hum Aapke Hain Kaun in 1994. She went on to act in a number of other films including Dil To Pagal Hai (1997).
She married Dr. Sriram Nene in 1999.
After marriage she starred in the movie Devdas which was India's nomination for the Foreign Films category of the Oscars.
Dixit gave birth to a baby boy Areen in 2003.