She married three times: The first time to James IV of Scotland, and their child became James V. The second time to Archibald Douglas 6th Earl of Angus, and their daughter Margaret Douglas was the mother of Henry Stuart, Lord Darnley who married Mary Queen of Scots and fathered James VI of Scotland. The third time to Henry Stuart Lord Methven.
She died of 'palsy' at Methven Castle, Perthshire. She was buried at the Carthusian Abbey of St John, Perth.
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