Melrose Place is an apartment block in the West Hollywood district of Los Angeles with young adults living in it. In the beginning, the story focused on how young people come to Los Angeles to realize their dreams. As time went by, more and more rich and powerful characters appeared and the focus was on their rivalry for power and money.
Dr. Michael Mancini, played by Thomas Calabro, was the only original character that stayed till the end. Jane Andrews Mancini, played by Josie Bissett, left for a while but returned. Amanda Woodward, played by Heather Locklear, stayed till the end, but she only joined in 1993.