The constellation covers a keystone-shaped wedge of sky stretching from approximately 4h to 7.5h of right ascension, and -71 to -85.5 degrees of declination. Other than the south polar constellation of Octans, it is the most southerly of constellations. As a result, it is essentially unobservable from the Northern Hemisphere. Besides those already mentioned, its other neighbouring constellations are Chamaeleon, Hydrus and Volans.
The first images taken by the Chandra X-Ray Telescope were of PKS 0637-752, a quasar in Mensa with a large gas jet visible in both optical and x-ray wavelengths.