Methotrexate
Methotrexate (formerly Amethopterin) is an antimetabolite originally used to treat many kinds of cancer. More recently it has come into use as a treatment for some
autoimmune diseases, including
psoriasis and
arthritis. It can be taken orally or by injection. Possible side effects can include
anemia, increased risk of bruising, and
nausea.
Chemically methotrexate is N-[4-(2,4-di[[amino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid.