The most famous cartographer of this family is Abraham Ortelius, author of the Theatre of the World (Theatrum Orbis Terrarum) atlas.
Abraham's sister, Orrilia Ortelius, was the wife of Sir Jacobus van Meteren and mother of historian Emanuel van Meteren.
Abraham's cousin Joachim Ortel (Ortelius) was a Dutch Agent and silk-merchant in London.
Links:
Amsterdam University Library - Abraham Ortelius online exhibit