Os mutantes was formed in Sao Paulo, Brazil in 1965 by brothers Arnaldo and Sergio Baptista along with their lead singer Rita Lee. They delivered five albums before Lee departed in 1972 to start her own solo career.
Though Os Mutantes did not spread into the popular commercial market, they did influence many English-speaking artists. For example, Kurt Cobain publicly requested a reunion tour from the trio in 1993, Beck released an experimental album called Mutations with the hit song Tropicalia, and David Byrne assembled Everything is Possible, the Os Mutantes' compilation album released by Luaka Bop in 1999.