Protagonistas de Novela has the same format and rules as Protagonistas de la Musica, and that is because Protagonistas de Novela, a reality show where the winners are guaranteed a spot in a future Spanish soap opera, was released before its musical version. Both shows are produced by Telemundo USA.
The female winner of the show's first season, Milly Ruperto, has already participated in a soap opera, playing a boxing trainer, alongside Venezuelan superstar Gaby Spanic.