Christian historians have claimed that in the last years of Emperor Philip the Arab (reigned 244 - 249), during otherwise undocumented festivities to commemorate the millennium of the founding of Rome (traditionally in 753 BCE, putting the date about 247), the fury of the Alexandrian mob rose to a great height, and when one of their poets prophesied a calamity, they committed bloody outrages on the Christians, whom the authorities made no effort to protect.
Dionysius, Bishop of Alexandria (247-265), relates the sufferings of his people in a letter addressed to Fabius, Bishop of Antioch, of which long extracts have been preserved in Eusebius' Historia Ecclesiae (I:vi: 41). After describing how a Christian man and woman, Metras and Quinta, were seized and killed by the mob, and how the houses of several other Christians were pillaged, Dionysius continues:
Apollonia and a whole group of early martyrs did not await the death they were threatened with, but either to preserve their chastity or because they were confronted with the alternative of renouncing their faith or suffering death, voluntarily embraced the death prepared for them, an action that runs perilously close to suicide, some thought. Saint Augustine touches on this question in the first book of the City of God, apropos of suicide (I:26):
The Roman Catholic Church celebrates Apollonia on February 9, and she is popularly invoked against the toothache because of the torments she had to endure. She is represented in art with pincers in which a tooth is held. In a late 14th century illumination from a French manuscript, widely distributed as a poster that is considered suitable for dentists' offices in the U.S., the sacred tooth in her pincers glows from within, like a lightbulb.
Saint Apollonia is one of the two patron saints of Catania. In Germany, where the fourteen saints (vierzehn heiligen) or Nothelfer are singled out as the patron saints of daily life, Apollonia, protectress against toothache, is one of them.
William S. Walsh, ''Curiosities of Popular Customs And of Rites, Ceremonies, Observances, and Miscellaneous Antiquities'' 1897, noted that, though the major part of her relics were preserved in the former church of St. Apollonia at Rome, her head at Santa Maria in Trastevere, her arms in St Lawrence Fuori le Mura, parts of her jaw in St. Basil's, and other relics are in the Jesuit church at Antwerp, in St. Augustine's at Brussels, in the Jesuit church at Mechlin, in St. Cross at Liege and in several churches at Cologne. These relics consist in some cases of a tooth only or a splinter of bone.
There was a church dedicated to her in Rome, near the Basilica di Santa Maria in Trastevere, but it no longer exists. Only its little square, the Piazza Sant' Apollonia remains.