Born in Shanghai, Soong was educated in the United States at the age of 14 in May 28, 1904. She returned to China in 1909 after graduating from Wesleyan College. In late 1911, she worked as a secretary for Sun Yat-sen, a job later succeeded by her sister, Soong Ching-ling. She met her future husband, Kung, in 1913, and married the following year in Yokohama. After marrying, Soong taught English for a while and engaged in child welfare work.
She went to the United States in the 1940s, and died later at the age of 83 in the New York-Presbyterian Hospital, New York.
Her children were: