The film was inspired by a series of children's novels by Margery Sharp.
The chemistry between the bumbling, nervous Bernard and the calm, assured Bianca works very well, and it is a little surprising that the film is not considered to be in the major league of Disney's animated features.
There was a sequel, The Rescuers Down Under (1990), set in the Australian outback. Bob Newhart and Eva Gabor reprised their roles from the first film, John Candy took the late Jim Jordan's place in the comical albatross role, playing the original albatross's brother, and George C. Scott played the villain, an animal smuggler. The Rescuers Down Under is notable for two landmarks in the history of Disney animated feature films: It was the first to use a computer-assisted production process, and it was the first sequel.
See also: List of fictional mice