Mozely was born at Gainsborough, Lincolnshire, the son of a bookseller and publisher. From Charterhouse School he progressed to Oriel College, Oxford, where he became the pupil, and subsequently the intimate friend, of John Henry Newman. In 1831 he was ordained, and in 1836 became rector of Cholderton, Wiltshire. From the beginning, he was a strong supporter of the Tractarian movement, and after contributing for some time to the British Critic, its periodical, succeeded Newman as editor in 1841.
In 1843 he was on the point of joining the Roman Catholic Church. Newman, however, strongly advised him to take two years to reflect, and Mozley decided to remain an Anglican. In 1844 he began to write leading articles for The Times, and continued to do so regularly for many years. In 1847 he resigned his country living and settled in London, but in 1868 accepted the living of Plymtree in Devon. From 1876-1880 he was rural dean of Ottery St Mary, Devon. He retired in 1880, and moved to Cheltenham, where he died.
He was the author of Reminiscences, chiefly of Oriel, and the Oxford Movement, published in 1882.
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