The museum was erected as part of the centenary celebrations of the engineer-statesman Sir M. Visvesarya (1861-1962). It was handed over to the Council of Scientific and Industrial Research (CSIR) in 1962.
Each floor of the museum is dedicated to a scientific discipline.
The Engine Hall exhibits used engines of various automobiles, machines used in industry, a jet aircraft engine, and other mechanical devices. The predictability and precision of mechanics is demonstrated by the rolling balls that travel endlessly within metal tracks without an external power source.
The Electro Technic Hall contains interactive electrical exhibits which work on the basic principles of electricity, electronics and communication.
The Fun Science Hall exhibits the sciences of sound, optics, fluids and perception.
The Space Hall is about rocket science and the history of space exploration.
The Dinosaur Corner has a moving replica of a Spinosaurus.
The museum attracts close to 1 million visitors each year.