On October 3, 1962, Schirra became the fifth American in space, piloting the Mercury 8 (Sigma 7) on a six-orbit mission lasting 9 hours, 13 minutes, and 11 seconds. The capsule attained a velocity of 17,557 miles per hour and an altitude of 175 statute miles.
On December 15, 1965, Schirra flew into space a second time in Gemini 6A, performing a docking maneuver with astronauts Frank Borman and James Lovell, Jr.
On October 11, 1968, Schirra flew into space a final time as commander of Apollo 7, the first manned flight in the Apollo program after a fatal fire during tests of Apollo 1. The three-man crew, including Donn Eisele and Walter Cunningham, performed rendezvous exercises with the upper stage of the Saturn 1-B launch vehicle and provided the first television pictures from a U.S. spacecraft.