During the years between 1799 and 1806 he spent short periods in a country lawyers office, a London West India merchants countinghouse, an Edinburgh solicitors chambers, and held the position of surgeon's mate on board H.M. guardship Gladiator in Portsmouth Harbour, under his uncle, who was surgeon.
He went to London in 1806, and became a newspaper reporter. He was in the lobby of the House of Commons on May 11, 1812 when Spencer Perceval was shot, and was the first to seize the assassin. By 1812 he had become editor of The Sun, a semi-official Tory paper; he occasionally inserted literary articles, then quite an unusual proceeding; but a quarrel with the chief proprietor brought that engagement to a close in 1817. He passed next to the editors chair of the Literary Gazette, which he conducted with success for thirty-four years.
Jerdan's position as editor brought him into contact with many distinguished writers. An account of his friends, among whom Canning was a special intimate, is to be found in his Men I have Known (1866). When Jerdan retired in 1850 from the editorship of the Literary Gazette his pecuniary affairs were far from satisfactory. A testimonial of over £900 was subscribed by his friends; and in 1853 a government pension of 100 guineas was conferred on him by Lord Aberdeen. He published his Autobiography in 1852-1853.
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