The movie was adapted by Larry Marcus, Billy Wilder, and Harry Kurnitz from the play by Agatha Christie. It was directed by Billy Wilder.
It was nominated for Academy Awards for Best Actor in a Leading Role (Charles Laughton), Best Actress in a Supporting Role (Elsa Lanchester), Best Director, Best Film Editing, Best Picture, and Best Sound.
Witness for the Prosecution was remade for television in 1982, starring Ralph Richardson, Deborah Kerr, Beau Bridges, Donald Pleasence, Wendy Hiller, and Diana Rigg. It was adapted by Lawrence B. Marcus and John Gay from the original screenplay and directed by Alan Gibson.