It was captured and destroyed by the emperor Julian in A.D. 363, but speedily rebuilt. It became a refuge for the Christian and Jewish colonies of that region, and there are said to have been 90,000 Jews in the place at the time of its capture by 'Ali in 657. The Arabs changed the name of the town to Anbar ("granaries").
Abu al-Abbas as-Saffah, the founder of the Abbasid caliphate, made it his capital, and such it remained until the founding of Baghdad in 762. It continued to be a place of much importance throughout the Abbasid period. It is now entirely deserted. The site is occupied only by ruin mounds. Their great extent indicates the former importance of the city.