Upon Jones' death in 1652, Webb inherited both a substantial fortune and library of drawings and designs, many of which dated back to Jones' influential travels to Italy.
The two architects share a connection with Greenwich, London. Webb designed King Charles Court in 1662, which later formed the first part of Greenwich Hospital, a short distance from the Queen's House, Jones' masterpiece at the foot of Greenwich Park. Webb also went on to design the enlargement of the Queen's House in 1662.
Further afield they also share a connection with Kingston Lacy, a stately home in Dorset where Webb supervised early works (c. 1660) on the building, following designs originally prepared by Jones.
Webb also designed the rebuild of Belvoir Castle in Leicestershire between 1654 and 1668.