William Lewis Cabell was born on 1 January 1827 in Danville, Virginia. Six of Cabell's brothers also held prominent positions in the Confederate Army. One other brother died just prior to the Civil War from an arrow wound received in Florida.
Cabell graduated from the United States Military Academy in 1850 and joined the United States Army as a second lieutenant with the 7th Infantry. In June of 1855 he was promoted to first lieutenant and appointed as regimental quartermaster on the staff of General Persifer F. Smith.
At the outbreak of the Civil War Cabell returned to Little Rock, Arkansas and offered his services to Governor Henry Massey Rector. During April of 1861 he received a telegram from the Confederate States government and went to Richmond, Virginia and assisted in the establishment of the commissary, quartermaster, and ordnance departments for the Confederate military.
He was sent to Manassas, Virginia to take the position of Quartermaster for the Confederate Army of the Potomac under General Pierre G.T. Beauregard. He served on Beauregard's staff and then on the staff of General Joseph E. Johnston until reassigned in January of 1862.
After leaving Virginia Cabell was assigned by General Albert Sidney Johnston to serve under General Earl Van Dorn who was commander of the Trans-Mississippi Department. Cabell was promoted to Brigadier General and placed in command of all Confederate troops on the White River with his headquarters at Jacksonport, Arkansas.
Soon after the Battle of Pea Ridge Confederate forces were withdrawn from Arkansas and moved across the Mississippi River. Upon arrival at Corinth, Mississippi Cabell was given command of a Texas brigade with an Arkansas regiment attached. Cabell led this brigade in several engagements around Corinth.
Cabell was transferred to an Arkansas brigade which he led in the Battle of Iuka, Battle of Saltillo, and the Battle of Corinth. Cabell was wounded leading a charge against the Union entrenchments at Corinth and again at the Battle of the Hatchie River Bridge which left him temporarily disabled and unfit for field command.
In February of 1863 he was placed in command of northwestern Arkansas and successfully recruited and outfitted one of the largest cavalry brigades west of the Mississippi. Cabell led this brigade in over 20 engagements in the Trans-Mississippi Department including prominent roles at the Battle of Poison Spring and the Battle of Marks' Mill where he commanded two brigades under General James Fleming Fagan.
Cabell was captured by Union forces in Missouri during Price's Missouri Raid on 25 October 1864 and was held as a prisoner of war at Johnson's Island Prison Camp on Lake Erie and at Fort Warren in Boston, Massachusetts.
After the war Cabell returned to Fort Smith, Arkansas where he worked as a civil engineer and studied law at night. He was admitted to the Arkansas bar in 1868 and practiced law for a few years. In 1872 Cabell and his family moved to Dallas, Texas and in 1874 he was elected Mayor of that city and served four terms in that position at various times. During his tenure he expanded rail access to the city, established sewer and electrical services, started a program of paving streets, and presided over a period of massive growth.
After leaving office, Cabell became Vice President of the Texas Trunk Railroad Company. In 1885 he was appointed US Marshall and served in that capacity until 1889. During the Spanish-American War, at age 71, he offered his military services to the US government.
Cabell also remained active in Confederate veterans affairs. Cabell oversaw several large veterans reunions, assisted in establishing veterans pensions, veterans homes, and Confederate cemeteries in Texas. He served as Commander of the Trans-Mississippi Department of the United Confederate Veterans.
William Lewis Cabell died on 21 February 1911 in Dallas, Texas. Cabell was buried in Dallas, Texas 5 days later after a heavily attended military parade.
Cabell's wife was the daughter of Major Elias Rector of Arkansas and served as a nurse during the Civil War.