July 30 - Indian Wars: Chief Pocatello of the Shoshone tribe signs the Treaty of Box Elder, promising to stop harassing the emigrant trails in southern Idaho and northern Utah.
October 15 - American Civil War: The first successful submarine, the CSS Hunley sinks during a test, killing Horace Lawson Hunley (its inventor) and a crew of seven.
November 17 - American Civil War: Siege of Knoxville begins - Confederate forces led by General James Longstreet place Knoxville, Tennessee under siege (the two week long siege and one failed attack was unsuccessful).
November 25 - American Civil War: Battle of Missionary Ridge - At Missionary Ridge in Tennessee, Union forces led by General Ulysses S. Grant break the Siege of Chattanooga by routing Confederate troops under General Braxton Bragg.
November 26 - American Civil War: Mine Run - Union forces under General George Meade position against troops led by Confederate General Robert E. Lee (Meade's forces could not find any weaknesses in the Confederate lines and give-up trying after five days).
November 27 - American Civil War: Confederate cavalry leader John Hunt Morgan and several of his men escape the Ohio state prison and return safely to the South.