He was the son of Casimir IV, King of Poland, and of Elizabeth of Bohemia. Wladislaw was married to Beatrice of Naples. His first child, son Louis II of Bohemia, was king of Hungary and Bohemia and was adopted by the emperor of the Holy Roman Empire in 1515. Wladislaw's daughter Anne of Bohemia b. 1503, was by imperial marriage contract in 1515 married to a grandson of Maximilian I Habsburg, emperor of the Holy Roman Empire.