Many third parties throughout U.S. history have achieved regional success and some (notably the Prohibition party and the Socialist Party of America) have had major portions of their platforms incorporated into the "major parties" platforms. While the parties in question did not go on to become one dominant players in American political life, their overall political platforms took root in the American political landscape.
Current major parties
Current "third" parties
Each of these five parties had ballot status for its presidential candidate in states with enough electoral votes to have a theoretical chance of winning in the last presidential election.
Other minor parties that have endorsed candidates
Historical political parties
Pre-Constitution
Pre-Jackson
Jacksonian Era
Civil War
Gilded Age
Progressive Era
20th century
Current and historical regional political parties
See: Party designation in early United States Congresses